Temple University Important Drug Drug PD Interactions Pharmacology Questions
Description
drug : ADALIMUMAB
Your draft should reflect an understanding of the material covered in weeks 5-10 and how it all relates to your drug of interest. At a minimum, your draft should include new information on the each of these topics:
- ADME properties of your drug
- Formulations & routes of administration
Distribution patterns in the body
General PK parameters (Vd, t1/2, Clearance rate, etc.)
- Metabolism & excretion of drugs, including key interactions with CYPs/transporters/etc.
Important drug-drug PK interactions?
- Likely & confirmed biological targets of the medication and the mechanism(s) of action
- Efficacy? Potency? Selectivity?
- Important drug-drug PD interactions?
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