Human research in scientific studies has a dark past. While not all scientific studies of the past were unethical, many were; and in present day, there are policies and procedures that researchers must follow to carry out ethical research.
For the Unit 2 Assignment, you will review historical human research studies that violated what are considered basic human rights when it comes to protecting research participants. You will also apply the four principles of ethical research to these historical research studies and discuss how the IRB process could have prevented these studies from violating human rights.

INSTRUCTIONS

Please review the “Introduction” and choose an article from “Section I: A Selected History of Research With Humans” in the Oxford Textbook of Clinical Research Ethics. Then, complete the following:

1. Provide a short summary of the article you chose and why you chose it.
2. Describe at least three ways the historical human research specifically violated each of the four principles of ethical research: autonomy, justice, beneficence, and nonmaleficence.
3. Discuss three ways the IRB process would have prevented the study from being carried out.

Assignment guidelines

You may complete the assignment in any of the following ways. Please be sure to review the minimum submission requirements for each option:

• A document, written as an APA formatted paper.
• Requirements:

For the document option:

• Your submission is composed in a Microsoft® Word® document.
• To meet the objective requirements, your response is at least 500 words in length.
• Your submission includes specific examples of concepts, topics, definitions, and other elements to demonstrate mastery of the objective.
• Your submission includes a highly developed viewpoint and purpose.
• Your response is in Standard English and demonstrates superior organization.
• Your communication is highly ordered, logical and unified, as well as original and insightful.
• Your submission displays exceptional content, organization, style, and mechanics.
• A separate page at the end of your response contains a list of references.
• Include both in-text and reference list citations where appropriate and reference all sources used following proper APA citation style.
• Please review the APA formatting and citation style in Academic Writer which can be found through Academic Tools.
• READING IS ATTACHED
• Reference – EZEKIEL J. EMANUEL et al.The Oxford Textbook of Clinical Research Ethics. Oxford: Oxford University Press, 2008. ISBN 9780195168655. Disponível em: https://search-ebscohost-com.libauth.purdueglobal.edu/login.aspx?direct=true&db=nlebk&AN=315325&site=eds-live. Acesso em: 31 mar. 2022.